麻豆原创

Enzymes Market Size and Share:

The global enzymes market size was valued at USD 13.97 Billion in 2024. Looking forward, IMARC Group estimates the market to reach USD 21.9 Billion by 2033, exhibiting a CAGR of 5.3% during 2025-2033. North America currently dominates the market, holding a market share of over 36.8% in 2024. The increasing demand for enzymes in food, healthcare, and biofuels, shifting focus on processing efficiency and product quality, surging sustainability concerns, and advancements in biotechnology are factors shaping the market's trajectory.

The healthcare and pharmaceutical sectors are key drivers for the enzymes market due to their critical role in diagnostics, therapeutics, and drug development. Total net spending on medicines in 2028 is expected to increase $127 Bn compared to 2023 in the United States. Over the next five years, medicine spending will grow between 6–9% on a list price basis and 4–7% after discounts and rebates. Enzymes such as proteases, lipases, and polymerases are integral in the synthesis of various active pharmaceutical ingredients (APIs) and the production of biologics, including monoclonal antibodies and vaccines. Moreover, the rising prevalence of chronic diseases has led to increased reliance on enzyme-based therapies, such as those used in enzyme replacement treatments for conditions like Gaucher’s disease and cystic fibrosis. The diagnostics field also benefits from enzymes like polymerases and reverse transcriptases, which are essential in molecular testing and the detection of infectious diseases.

The United States is known to be a major market disruptor for enzymes. There have been introductions in personalized medicine initiatives and advances in gene therapy that bolster the product's demand, as they are critical in clustered regularly interspaced short palindromic repeats (CRISPR) and other genome-editing technologies. According to IQVIA’s tally, 114 gene therapy trials were started in the year 2023, a large majority (88 of 114, or 77%) of which were sponsored by the healthcare industry. As per the U.S. Department of Health and Human Services, there are now more than 50 certified centers in the U.S. that focus on delivering gene therapies. Enzymes have the ability to enhance precision, reduce side effects, and improve therapeutic outcomes, which underscores their growing importance in modern healthcare.

Enzymes Market Trends:

Increasing demand for enzymes across industries

The enzymes market experiences a robust impetus driven by heightened demand across diverse industries. One of the primary applications of enzymes is in food and beverage (F&B) industries where they are used for processing efficiency, quality improvement, and product innovation. Enzymes play an important role in improving food texture and taste as well as enhancing nutrition. Likewise, enzymes are extensively utilized in healthcare with regard to diagnostics, drugs, and treatments. Dealing with waste conversion into biofuels, enzymes catalyze organic matter transformation for the use of renewable energy sources. This increased demand reemphasizes the need for enzymes as it addresses industrial efficiency and innovations across sectors.

Sustainability and environmentally friendly solutions

One of the most important drivers of the enzymes market is the growing global focus on sustainability and environmentally friendly options. Enzymes convert conventional chemical processes into greener alternatives that rely less on harsh chemicals and reduce waste production. According to UNEP, municipal solid waste generation is expected to increase from 2.1 billion tons in 2023 to 3.8 billion tons by 2050. This coincides with increasing consumer and regulatory demand for eco-friendly products and processes. Enzymes enable compliance with environment-friendly regulations while ensuring product quality and process efficiency. Presently, this has a positive influence on enzyme acceptance across various applications and markets their demand as key components of the sustainable industrial landscape.

Advances in biotechnology and genetic engineering

New, rapid strides in biotechnology and genetic engineering have given rise to a novel phase of enzyme development and utilization. According to the biotech interest group ISAAA, genetically modified (GM) crops in the year 2018 grew to cover about 191.7 million hectares. Nowadays, it is feasible for scientists to engineer enzymes for specific uses within industries. This advancement has broadened the horizon in terms of enzymes and their possible applications. Stable, more active, and highly specific engineered enzymes have created possibilities in industries where enzyme-based processes did not exist. Moreover, enzymes from recombinant DNA technology are known to be more scalable and cheaper. This intersection of biotechnology and enzymes enriches industrial processes as well as allows the adaptability of enzymes to modern technological advances, thus fueling their integration across various sectors.

Enzymes Industry Segmentation:

IMARC Group provides an analysis of the key trends in each segment of the global enzymes market, along with forecast at the global, regional, and country levels from 2025-2033. The market has been categorized based on the type, source, reaction type, and application.

Analysis by Type:

• Protease
• Carbohydrase
• Lipase
• Polymerase and Nuclease
• Others

Carbohydrase stand as the largest component in 2024, holding around 46.8% of the market. The carbohydrase segment is fuelling the rising need for healthy and nutritious food. These enzymes catalyse the breakdown of complex carbohydrates into simple sugar molecules, thereby helping to digest and absorb the complex carbohydrates. Besides, there is increasing use of such enzymes by industries that make gluten-free products because of the rising incidence of dietary intolerances such as gluten intolerance. Along with this, the biofuel and bioenergy industries use this enzyme for converting lignocellulosic biomass into fermentable sugars which are processed into different biofuels thereby complementing sustainability efforts and the search for renewable energy sources. Moreover, recent advancements in enzyme engineering and biotechnology allow customizing carbohydrases for specific applications which may further increase carbohydrases' efficiency and effectiveness.

 Analysis by Source:

• Microorganisms
• Plants
• Animals

Microorganisms leads the market with around 85.2% of market share in 2024. The microorganism segment is driven by several paramount drivers, such as the increasing demand for sustainable solutions from several industries, including agriculture, food and beverages (F&B), and waste management. These microorganisms offer environmental alternatives in terms of crop protection, suffusing and enhancing soil fertility, and composting biodegradable waste. Also, developments in biotechnology and genetic engineering have made it very feasible for scientists to tap microorganisms for a plethora of applications like biopesticides and probiotics. This trend further boosts their usage and market demand. Not only this, the importance of clean energy sources also adds to the popularity of this product as they find application in microbes for biofuel breeding and renewable energy. Furthermore, collaboration programs between research institutions and industries will yield innovation and create novel applications and products that utilize the unique properties of microorganisms. Amidst these growing trends, raising awareness on the microcosmic setting will add pressure on the use for microorganism-based solutions as it proves to be a potential engine to broaden this market.

Analysis by Reaction Type:

• Hydrolase
• Oxidoreductase
• Transferase
• Lyase
• Others

. The hydrolase segment's popularity stems from its use in different industries, including food and beverages, detergents, and pharmaceuticals. Because of their ability to catalyze hydrolysis of a substrate into simple compounds, they are used in all processes where it is advantageous to further enhance production efficiencies and quality. Consequently, with the rising trend toward greener consumer options, they are gaining popularity as they are able to biodegrade waste and lessen it through hydrolysis. Moreover, the continued advent in biotechnology and protein engineering have given rise to engineered hydrolases with higher efficiency and specificity, and therefore broadened their applications. Cross-sectoral partnerships also bring forth innovations, which then open opportunities for making hydrolases fit for niche processes.

Analysis by Application:

• Food and Beverages
• Household Care
• Bioenergy
• Pharmaceutical and Biotechnology
• Feed
• Others

Food and beverages lead the market with around 78.9% of market share in 2024. The food and beverage industry's dominance is based on a number of parameters that dictate the trajectory of its growth. Enzymes are indispensable in food processing, as they increase the quality, flavor, and nutrition of the products. They help in breaking complex molecules to help in the manufacture of products such as cheese, bread, and drinks. The increased demand for clean labels and natural ingredients in food products drives the use of enzymes, as these act as a sustainable substitute for chemical additives. Enzymes help in shortening the processing time and reducing energy consumption, thus presenting the industry with avenues toward efficiency. Moreover, the trend of personalization in nutrition and functional food further aggravates the development of enzymes for their potency to promote absorption and digestion of nutrients. Due to the increasing consciousness of consumers over health, enzymes thus add to making products with better nutritional value possible. This convergence of consumer preferences, efficiency enhancements, and nutritional advancements collectively drive the use of enzymes in the food and beverage segment, underpinning its sustained growth.

Regional Analysis:

• North America
  • United States
  • Canada
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Indonesia
  • Others
• Europe
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Russia
  • Others
• Latin America
  • Brazil
  • Mexico
  • Others
• Middle East and Africa

In 2024, North America accounted for the largest market share of over 36.8%. The major driving factors influencing the market for enzymes in North America are the region's strong industrial base, which demands enzymes in different sectors, including food and beverages, pharmaceuticals, biofuels, and their use for process optimization, product quality development, and innovation. Enzymes are also being considered because of the increasing consumer awareness of sustainability and green alternatives associated with stringent environmental regulations. Coupled with this, biotechnology and genetic engineering have furthered the development of specific enzymes that have accurate functional applications, resulting in added scope and penetration into the market. The combination of industrial demand and research also enhances enzyme innovation and commercialization. The booming biopharma sector additionally provides speed and terrain towards increased enzyme demands for development and manufacturing. Moreover, the development in enzyme-related research and activities makes North America a great player in the market.

Key Regional Takeaways:

United States Enzymes Market Analysis

The enzymes market in the United States is experiencing robust growth driven by advancements in biotechnology and increasing demand across diverse industries such as food and beverages, pharmaceuticals, and biofuels. The rising consumer preference for clean-label products has encouraged food manufacturers to incorporate enzymes for improving food quality and shelf-life, fueling market expansion. Additionally, the growing awareness of the health benefits of enzymes, particularly in digestive aids and dietary supplements, is supporting demand in the healthcare sector. According to a journal, around 5.3 Million people in the United States take non-prescription digestive enzymes, reflecting the increasing reliance on enzyme-based supplements for digestive health. Technological innovations in enzyme production, such as recombinant DNA technology, are enhancing enzyme efficiency and specificity, further driving market growth. Furthermore, the increasing adoption of sustainable practices across various industries is contributing to the demand for enzymes in industrial applications like detergents, textiles, and agriculture. Government initiatives supporting research and development in biotechnology are also expected to propel the enzymes market in the country.

Asia Pacific Enzymes Market Analysis

The Asia-Pacific (APAC) region is experiencing significant growth in the enzymes market, driven by the expanding food and beverage industry, particularly in countries like India and Japan. In India, the rise in disposable personal income is contributing to the market’s growth. According to Ministry of Statistics and Programme Implementation (MOSPI), disposable personal income in India increased by 8.42% in 2023, compared to 2022. This growing purchasing power, along with rising demand for processed and functional foods, is driving the need for enzymes in food production. Additionally, rapid industrialization and a growing emphasis on sustainable production practices are increasing the adoption of enzymes in manufacturing processes, including textiles, detergents, and biofuels. The pharmaceutical sector in APAC is also contributing to market growth, with a rising need for enzyme-based therapies and supplements. These factors combined make the APAC region a key player in the global enzymes market.

Europe Enzymes Market Analysis

The enzymes market in Europe is experiencing significant growth, largely driven by the increasing demand for enzymes in the food and beverage industry. With a growing consumer preference for clean-label, natural ingredients, manufacturers are increasingly incorporating enzymes into production to enhance food quality and minimize the use of artificial additives. Enzymes are also becoming more popular in the creation of functional foods and beverages, as they improve nutritional value and digestibility. The rising focus on sustainable and eco-friendly production methods is further boosting the demand for enzymes across sectors such as textiles, detergents, and biofuels. The pharmaceutical industry is another important contributor, as enzymes play a role in developing therapies for conditions like cancer, metabolic disorders, and digestive issues. Moreover, sustainability is gaining momentum in Europe’s major markets, including France, Germany, Italy, and the UK, with over 66% of consumers planning to make a sustainable major purchase in the next year willing to pay a premium for it. Europe’s commitment to environmental regulations and sustainability is encouraging industries to adopt biocatalysts like enzymes, which offer energy-efficient, low-waste solutions. Furthermore, increased public and private investment in research and development is expected to drive further innovation in the enzymes market.

Latin America Enzymes Market Analysis

In Latin America, the enzymes market is driven by the expanding food and beverage industry, with increasing demand for processed foods and nutritional products. Ultra-processed foods and drinks account for around 20-30% of the calories consumed across the region, contributing to the rising need for enzymes to improve food quality, shelf life, and nutritional value. Additionally, the growing interest in functional foods, which offer added health benefits, is further boosting the use of enzymes in food production. The rise of biotechnology applications in agriculture and biofuels is also supporting market growth. As economic conditions improve and disposable incomes rise, the enzymes market is expected to continue expanding in Latin America.

Middle East and Africa Enzymes Market Analysis

The enzymes market in the Middle East and Africa (MEA) is growing significantly as industrial sectors such as food and beverage processing, detergents, and biofuels are expanding. Another major driver is the growing focus on sustainability. Enzymes are increasingly being used in eco-friendly processes, such as bio-based plastics production and wastewater treatment, in line with the region's commitment to environmental sustainability and green technologies. For example, Saudi Arabia's Vision 2030 and the UAE's initiatives toward reducing environmental impact and diversifying their economies create a strong demand for enzymatic processes in industries that prioritize sustainability. Additionally, advancements in biotechnology and enzyme technology are enhancing the production and efficiency of enzymes, thus lowering costs and making them more accessible to industries in the region. The biofuel industry is also expanding, with enzymes playing a vital role in the conversion of biomass to fuel, aligning with global trends toward renewable energy sources.

Competitive Landscape:

The major players in the enzymes market are focusing on strategic initiatives such as expanding production capacity, advancing research and development, and forming collaborative partnerships to meet the growing demand for enzyme applications across various industries. Companies are enhancing their capabilities to deliver innovative and sustainable enzyme solutions, particularly for sectors like food and beverages (F&B), biofuels, and healthcare. Moreover, efforts are also directed towards improving enzyme efficiency, stability, and specificity, catering to evolving industrial requirements and consumer preferences. Besides this, significant investments in technology and infrastructure underscore their commitment to addressing challenges in sustainability and environmental compliance, while aligning with market trends such as clean-label products and renewable energy.

The report provides a comprehensive analysis of the competitive landscape in the enzymes market with detailed profiles of all major companies, including:

• Advanced Enzyme Technologies Limited
• Amano Enzyme Inc.
• Associated British Foods plc
• Aumgene Biosciences
• BASF SE
• Chr. Hansen Holding A/S
• Codexis Inc.
• DuPont de Nemours Inc.
• Koninklijke DSM N.V.
• Novozymes A/S
• Novus International Inc. (Mitsui & Co. Ltd.)
• Thermo Fisher Scientific Inc

Latest News and Developments:

• September 2024: Ligo Biosciences is advancing deep-learning models for enzyme design to reduce the cost of chemical manufacturing. The USD 6 Trillion chemical industry contributes 20% of industrial greenhouse gases and 15% of global energy usage. Enzymes provide a more sustainable alternative to traditional chemical synthesis but typically require years of development. Ligo’s enzyme models accelerate this process by learning the principles of catalysis, enabling enzyme design for specific reactions in days, not years.
• August 2024: Twist Bioscience Corporation and bitBiome Inc., have launched a joint Transaminase Enzyme Screening Kit, featuring a curated collection of 48 diverse transaminase enzymes for in-house screening and evaluation. Transaminases, which catalyze the transfer of amine groups, are gaining attention for their potential in synthesizing chiral amines which are key building blocks in pharmaceuticals by offering a more sustainable alternative to traditional synthesis methods.
• July 2024: EnPlusOne Biosciences, Inc., a biotechnology company focused on enzyme-driven RNA synthesis, announced the successful synthesis of the antisense strand of the siRNA drug Leqvio® (inclisiran), a treatment for hypercholesterolemia. Licensed from Alnylam Pharmaceuticals and marketed by Novartis, Leqvio® targets a large patient population and represents a significant milestone in RNA-based therapeutics.
• May 2024: Fermbox Bio, a synthetic biology firm, has introduced EN3ZYME, a next-gen enzyme formulation engineered to enhance the conversion of pre-treated agricultural residues into fermentable cellulosic sugars. These sugars enable the production of 2G ethanol and serve as carbon feedstock for precision fermentation applications, including bio-based proteins, flavors, and colorants. The innovation promotes a circular bioeconomy while mitigating the food-vs-fuel challenges linked to 1G ethanol.
• July 2023: Codexis, Inc., a leader in enzyme engineering, announced a strategic shift to focus on its Enzyme-Catalyzed Oligonucleotide (ECO) Synthesis™ platform and its Pharmaceutical Manufacturing business. To streamline operations, the company will discontinue certain biotherapeutic development programs, consolidate operations at its headquarters, and reduce its workforce by approximately 25%.

Enzymes Market Report Scope:

Key Benefits for Stakeholders:

• IMARC’s report offers a comprehensive quantitative analysis of various market segments, historical and current market trends, market forecasts, and dynamics of the enzymes market from 2019-2033.
• The research study provides the latest information on the market drivers, challenges, and opportunities in the global enzymes market.
• The study maps the leading, as well as the fastest-growing, regional markets. It further enables stakeholders to identify the key country-level markets within each region.
• Porter's Five Forces analysis assists stakeholders in assessing the impact of new entrants, competitive rivalry, supplier power, buyer power, and the threat of substitution. It helps stakeholders to analyze the level of competition within the enzymes industry and its attractiveness.
• Competitive landscape allows stakeholders to understand their competitive environment and provides an insight into the current positions of key players in the market.